The human nervous system communicates through a series of electrical impulses called action potentials. These signals allow our brain to control many key body functions, such as telling muscles to contract or deliver sensory information about the surrounding environment. At their core, however, these action potentials are still just electrical impulses. By artificially applying these electrical impulses, neuromodulation allows communication with the nervous system using its native language. In short, neuromodulation uses the natural response of the body, rather than engineered foreign molecules, to provide therapy.

NMT’s revolutionary transdermal neuromodulation platform provides a precise, focused, and controlled level of electrical stimulation to targeted peripheral nerves. It is postulated, that for emesis, stimulation of the median nerve causes activation of pathways that innervate the higher control centers of the brain. These areas of the brain are responsible for regulating many key autonomic functions of the body, including gastric arrhythmia. NMT’s transdermal devices stimulate these nerves and appropriately modulate various physical pathways to achieve the desired clinical effect.

The technology and science behind NMT’s product line was specifically developed to provide these electrical signals with patient efficacy, use, and safety being paramount. NMT’s product platform achieves a high level of efficacy while using a fraction of the energy found in other neuromodulation technologies. This eliminates many of the limitations of previous electrical stimulation devices such as skin/nerve damage, ensuring patient comfort and safety.

The NMT proprietary pulse and waveform is specifically designed to reduce nerve habituation (i.e. decreased nerve sensitivity). This prevents patients from becoming resistant to the therapy over time and maintains efficacy without increasing the stimulus.

Additionally, the NMT devices can all be described as “constant current” devices, ensuring minimal device output with maximum benefit to the patient.

All of NMT’s devices are designed to put the patient in complete control of their therapy, while providing safe, rapid, and reliable relief of their symptoms.